PeneloPET simulations of the Biograph ToF clinical PET scanner

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dc.contributor.author Abushab, K. M.
dc.contributor.author Herraiz, J. L.
dc.contributor.author España, Samuel
dc.contributor.author Vaquero López, Juan José
dc.contributor.author Jakoby, B. W.
dc.contributor.author Udías, José Manuel
dc.contributor.author Vicente, Esther
dc.date.accessioned 2015-03-02T11:53:29Z
dc.date.available 2015-03-02T11:53:29Z
dc.date.issued 2011
dc.identifier.bibliographicCitation 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC): Valencia, Spain. 23-29 October 2011 (2011). IEEE, 3311-3313.
dc.identifier.isbn 978-1-4673-0118-3
dc.identifier.issn 1082-3654
dc.identifier.uri http://hdl.handle.net/10016/20118
dc.description Proceedings of: 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). Valencia, Spain, 23-29 October 2011
dc.description.abstract Monte Carlo simulations are widely used in positron emission tomography (PET) for optimizing detector design, acquisition protocols, as well as for developing and assessing corrections and reconstruction methods. PeneloPET is a Monte Carlo code for PET simulations which considers detector geometry, acquisition electronics and materials, and source definitions. PeneloPET is based on PENELOPE, a Monte Carlo code for the simulation of the transport in matter of electrons, positrons and photons, with energies up to 1 GeV. In this work we use PeneloPET to simulate the Biograph TruePoint (B-TP), Biograph TruePoint with TrueV (B-TPTV) and Biograph mCT PET/CT scanners. These configurations consist of three (B-TP) and four (B-TPTV and mCT) rings of 48 detector blocks. Each block comprises a 13 × 13 matrix of 4 × 4 × 20 mm3 LSO crystals. Simulations were adjusted to reproduce some experimental results from the actual scanners and validated by comparing their predictions to further experimental results. Sensitivity, spatial resolution, noise equivalent count (NEC) rate and scatter fraction (SF) were estimated. The simulations were then employed to estimate the optimum values of system parameters, such as energy and time coincidence windows and to assess the effect of system modifications (such as number of rings) on performance.
dc.description.sponsorship This work was supported in part by Comunidad de Madrid (ARTEMIS S2009IDPI 1802), Spanish Ministry of Science and Innovation (ENTEPRASE Grant, PSE 300000 2009 5) and PRECISION grant IPT 300000 2010 3 and european regional funds and CPAN, Centro de Fisica de Particulas, Astroparticulas y Nuclear (CSD 2007 00042@Ingenio2010 12). This study has been (partially) funded by CDTI under the CENIT Programme (AMIT Project). Part of the calculations of this work was performed in the "Cluster de Calculo de Alta Capacidad para Tecnicas Fisicas "funded in part by UCM and in part by UE with European regional funds"
dc.format.extent 9
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Ieee - The Institute Of Electrical And Electronics Engineers, Inc
dc.rights © 2011 IEEE.
dc.subject.other Monte Carlo methods
dc.subject.other Biomedical electronics
dc.subject.other Image scanners
dc.subject.other Lithium compounds
dc.subject.other Optimisation
dc.subject.other Positron emission tomography
dc.subject.other Sensitivity
dc.title PeneloPET simulations of the Biograph ToF clinical PET scanner
dc.type conferenceObject
dc.type bookPart
dc.description.status Publicado
dc.relation.publisherversion http://dx.doi.org/10.1109/NSSMIC.2011.6153852
dc.subject.eciencia Biología y Biomedicina
dc.subject.eciencia Medicina
dc.identifier.doi 10.1109/NSSMIC.2011.6153852
dc.rights.accessRights openAccess
dc.relation.projectID Comunidad de Madrid. S2009/DPI-1802/ARTEMIS
dc.type.version acceptedVersion
dc.relation.eventdate 23-29 October 2011
dc.relation.eventplace Valencia, España
dc.relation.eventtitle 2011 IEEE Nuclear Science Symposiun and Medical Imaging Conference (NSS-MIC)
dc.relation.eventtype proceeding
dc.identifier.publicationfirstpage 4420
dc.identifier.publicationlastpage 4428
dc.identifier.publicationtitle 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC): Valencia, Spain. 23-29 October 2011 (2011). IEEE, 4420-4428.
dc.identifier.uxxi CC/0000022636
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