Publication:
Preparation, thermoresponsive behavior, and preliminary biological study of functionalized poly(N-isopropylacrylamide-co-dopamine methacrylamide) copolymers with an organotin(IV) compound

Simple item page
dc.affiliation.dptoUC3M. Departamento de Ciencia e Ingeniería de Materiales e Ingeniería Químicaes
dc.affiliation.grupoinvUC3M. Grupo de Investigación: Polímeros y Compositeses
dc.contributor.authorGarcía Peñas, Alberto
dc.contributor.authorWang, Yu
dc.contributor.authorMena Palomo, Irene
dc.contributor.authorLopez Collazo, Eduardo
dc.contributor.authorDíaz García, Diana
dc.contributor.authorGomez Ruiz, Santiago
dc.contributor.authorStadler, Florian J.
dc.contributor.funderComunidad de Madrides
dc.contributor.funderMinisterio de Ciencia, Innovación y Universidades (España)es
dc.date.accessioned2023-06-14T12:45:52Z
dc.date.available2023-06-14T12:45:52Z
dc.date.issued2021-02-01
dc.description.abstractRecent advances focused on smart polymers have demonstrated the numerous advantages regarding other structures because they can adapt the behavior depending on physicochemical properties. In this way, functionalized thermoresponsive polymers with organometallic complexes were profoundly analyzed. Consequently, novel catalytic systems or biomedical devices could be developed. This publication focuses on the facile preparation of poly(N-isopropylacrylamide-co-dopamine methacrylamide) copolymers functionalized with triphenyltin chloride by protonolysis through the -OH of catechol groups. The presence of hydrophobic organotin(IV) derivatives could modify the solubility, thermoresponsive behavior, and other properties regarding pure copolymers. Also, sensitive analysis of the microstructure could help to understand the changes associated with the lower critical solution temperature by rheology, UV-vis spectroscopy, and calorimetry. In addition, a preliminary biological study against MDA-MB-231 cancer cells and peripheral blood mononuclear cells showed that the functionalized copolymers could be a potential platform to be explored in the future in the fight against cancer.en
dc.description.sponsorshipThe financial support obtained from the National Science Foundation of China (21574086), Shenzhen Fundamental Research Funds (No. KC2014ZDZJ0001A), Shenzhen Sci & Tech research grant (ZDSYS201507141105130) and China Postdoctoral Science Foundation Grant (2018M633119) are acknowledged. Also, these researchers would like to thank the former Ministerio de Ciencia, Innovación y Universidades of Spain (current Ministerio de Ciencia e Innovación of Spain) for the grant RTI2018-094322-B-I00 and the Dirección General de Investigación e Innovación, Consejería de Educación e Investigación de la Comunidad de Madrid for the predoctoral grant PEJD-2017-PRE/BMD-3512 (I. M.-P.).en
dc.format.extent10es
dc.identifier.bibliographicCitationGarcía-Peñas, A., Wang, Y., Mena-Palomo, I., López-Collazo, E., Díaz-García, D., Gómez-Ruiz, S., & Stadler, F. J. (2021). Preparation, thermoresponsive behavior, and preliminary biological study of functionalized poly(N-isopropylacrylamide-co-dopamine methacrylamide) copolymers with an organotin(IV) compound. Polymer Testing, 94, 107046.en
dc.identifier.doihttps://doi.org/10.1016/j.polymertesting.2020.107046
dc.identifier.issn0142-9418
dc.identifier.publicationfirstpage1es
dc.identifier.publicationissue107046es
dc.identifier.publicationlastpage10es
dc.identifier.publicationtitlePolymer Testingen
dc.identifier.publicationvolume94es
dc.identifier.urihttps://hdl.handle.net/10016/37488
dc.identifier.uxxiAR/0000026867
dc.language.isoengen
dc.publisherElsevieren
dc.relation.projectIDGobierno de España. RTI2018-094322-B-I00es
dc.relation.projectIDComunidad de Madrid. PEJD-2017-PRE/BMD-3512es
dc.rights© 2020 Published by Elsevier Ltden
dc.rightsAtribución-NoComercial-SinDerivadas 3.0 España*
dc.rights.accessRightsopen accessen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.subject.ecienciaMaterialeses
dc.subject.ecienciaQuímicaes
dc.subject.otherBiocompatibilityen
dc.subject.otherThermoresponsive polymersen
dc.subject.otherOrganotin(Iv) derivativesen
dc.subject.otherFunctionalized structuresen
dc.titlePreparation, thermoresponsive behavior, and preliminary biological study of functionalized poly(N-isopropylacrylamide-co-dopamine methacrylamide) copolymers with an organotin(IV) compounden
dc.typeresearch article*
dc.type.hasVersionVoR*
dspace.entity.typePublication
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
preparation_PT_2021.pdf
Size:
1.58 MB
Format:
Adobe Portable Document Format
Download
Collections
DCIMIQ - CIMIQ - PC - Artículos de Revistas