Publication: Tuning the cell and biological tissue environment through magneto-active materials
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2021-09-19
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Tutors
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MDPI
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Abstract
This review focuses on novel applications based on multifunctional materials to actuate
biological processes. The first section of the work revisits the current knowledge on mechanically
dependent biological processes across several scales from subcellular and cellular level to the cellcollective
scale (continuum approaches). This analysis presents a wide variety of mechanically
dependent biological processes on nervous system behaviour; bone development and healing;
collective cell migration. In the second section, this review presents recent advances in smart
materials suitable for use as cell substrates or scaffolds, with a special focus on magneto-active
polymers (MAPs). Throughout the manuscript, both experimental and computational methodologies
applied to the different treated topics are reviewed. Finally, the use of smart polymeric materials in
bioengineering applications is discussed.
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Keywords
Biomechanics, Mechanobiology, Magneto-active polymers (MAP), Magnetorheological elastomers, Ferrogels, Constitutive modelling, Cell migration, Tissue remodelling, 3D printing
Bibliographic citation
Applied Sciences, 2021, 11(18): 8746.