Publication:
Highly integrated autonomous lab-on-a-chip device for on-line and in situ determination of environmental chemical parameters

dc.affiliation.dptoUC3M. Departamento de Ciencia e Ingeniería de Materiales e Ingeniería Químicaes
dc.affiliation.grupoinvUC3M. Grupo de Investigación: Síntesis y Procesado de Materialeses
dc.contributor.authorMartínez Cisneros, Cynthia Susana
dc.contributor.authorDa Rocha, Zaira
dc.contributor.authorSeabra, Antonio
dc.contributor.authorAlonso Chamarro, Julián
dc.contributor.authorValdés, Francisco
dc.contributor.funderMinisterio de Economía y Competitividad (España)es
dc.date.accessioned2023-12-13T15:43:30Z
dc.date.available2023-12-13T15:43:30Z
dc.date.issued2018-07-01
dc.description.abstractThe successful integration of sample pretreatment stages, sensors, actuators and electronics in microfluidic devices enables the attainment of complete micro total analysis systems, also known as lab-on-a-chip devices. In this work, we present a novel monolithic autonomous microanalyzer that integrates microfluidics, electronics, a highly sensitive photometric detection system and a sample pretreatment stage consisting on an embedded microcolumn, all in the same device, for on-line determination of relevant environmental parameters. The microcolumn can be filled/emptied with any resin or powder substrate whenever required, paving the way for its application to several analytical processes: separation, pre-concentration or ionic-exchange. To promote its autonomous operation, avoiding issues caused by bubbles in photometric detection systems, an efficient monolithic bubble removal structure was also integrated. To demonstrate its feasibility, the microanalyzer was successfully used to determine nitrate and nitrite in continuous flow conditions, providing real time and continuous information.en
dc.description.sponsorshipAuthors would like to acknowledge the Spanish MINECO and the Catalonia Government for their financial support through the projects CTQ2017-85011R and 2017 SGR220, respectively. Partial financial support from Met-Mex Pefioles is also acknowledged.en
dc.description.statusPublicadoes
dc.format.extent6
dc.identifier.bibliographicCitationLab on a chip (2018), 18(13), 1884-1890.en
dc.identifier.doihttps://doi.org/10.1039/c8lc00309b
dc.identifier.issn1473-0197
dc.identifier.publicationfirstpage1884
dc.identifier.publicationissue13
dc.identifier.publicationlastpage1890
dc.identifier.publicationtitleLAB ON A CHIPen
dc.identifier.publicationvolume18
dc.identifier.urihttps://hdl.handle.net/10016/39083
dc.identifier.uxxiAR/0000021666
dc.language.isoengen
dc.publisherRoyal Society of Chemistryen
dc.relation.projectIDGobierno de España. CTQ2017-85011Res
dc.rightsThis journal is © The Royal Society of Chemistry 2018.en
dc.rights.accessRightsopen accessen
dc.subject.ecienciaMaterialeses
dc.subject.otherLab-on-a-chipen
dc.subject.otherPhotometric detectionen
dc.subject.otherEnvironmental parametersen
dc.titleHighly integrated autonomous lab-on-a-chip device for on-line and in situ determination of environmental chemical parametersen
dc.typeresearch article*
dc.type.hasVersionAM*
dspace.entity.typePublication
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