Publication:
A New Workflow for Image-Guided Intraoperative Electron Radiotherapy Using Projection-Based Pose Tracking

Simple item page
dc.affiliation.dptoUC3M. Departamento de Bioingenieríaes
dc.affiliation.grupoinvUC3M. Grupo de Investigación: BSEL - Laboratorio de Ciencia e Ingeniería Biomédicaes
dc.contributor.authorGoswami, Subhra S.
dc.contributor.authorOrtuño, Juan E.
dc.contributor.authorSantos, Andrés
dc.contributor.authorCalvo, Felipe A.
dc.contributor.authorPascau González-Garzón, Javier
dc.contributor.authorLedesma Carbayo, María Jesús
dc.contributor.funderMinisterio de Economía y Competitividad (España)es
dc.contributor.funderMinisterio de Ciencia, Innovación y Universidades (España)es
dc.date.accessioned2021-03-02T11:31:19Z
dc.date.available2021-03-02T11:31:19Z
dc.date.issued2020-07-27
dc.description.abstractA new workflow is proposed to update the intraoperative electron radiotherapy (IOERT) planning refreshing the position and orientation (pose) of a virtual applicator with respect to the preoperative computed tomography (CT) with the actual pose during surgery. The workflow proposed relies on a robust registration of the preoperative CT and intraoperative projection radiographs acquired with a C-arm system. The workflow initially performs a geometric calibration of the C-arm using fiducials placed on the applicator. In the next step, a point-based 2D-3D registration based on fiducials positioned on the patient's skin is performed, followed by an intensity-based registration that refines the point-based registration result. The performance of the workflow has been evaluated using a realistic physical phantom consisting of a pig lower limb and its corresponding CT and 7 C-arm projections at different poses. The accuracy has been measured with respect to the applicator origin and axis before and after the registration refinement process. A feasibility study with human data is also included. Error analysis revealed angular accuracy of 0.9 ± 0.7 degrees and translational accuracy of 1.9 ± 1 mm. Our experiments demonstrated that the proposed workflow can achieve subdegree angular accuracy in locating the applicator with respect to the preoperative CT to update and supervise the IOERT planning right before radiation delivery. The proposed workflow could be easily implementable in a routine, corresponding to a significant improvement in quality assurance during IOERT procedures.en
dc.format.extent16
dc.identifier.bibliographicCitationGoswami, S. S., Ortuno, J. E., Santos, A., Calvo, F. A., Pascau, J., Ledesma-Carbayo, M. J. (2020). A New Workflow for Image-Guided Intraoperative Electron Radiotherapy Using Projection-Based Pose Tracking. IEEE Access, 8, 137501–137516.en
dc.identifier.doihttps://doi.org/10.1109/access.2020.3011915
dc.identifier.issn2169-3536
dc.identifier.publicationfirstpage137501
dc.identifier.publicationlastpage137516
dc.identifier.publicationtitleIEEE Access
dc.identifier.publicationvolume8
dc.identifier.urihttps://hdl.handle.net/10016/32067
dc.identifier.uxxiAR/0000026499
dc.language.isoeng
dc.publisherIEEE
dc.relation.projectIDGobierno de España. TEC2015-66978-Res
dc.relation.projectIDGobierno de España. RTI2018-098682-B-I00es
dc.rights© 2020 by the authors.en
dc.rightsAtribución 3.0 España*
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subject.ecienciaBiología y Biomedicinaes
dc.subject.other3d-2d registrationen
dc.subject.otherIGIOERTen
dc.subject.otherImage guided intra operative electron radiotherapyen
dc.subject.otherIOERTen
dc.subject.otherIORTen
dc.titleA New Workflow for Image-Guided Intraoperative Electron Radiotherapy Using Projection-Based Pose Trackingen
dc.typeresearch article*
dc.type.hasVersionVoR*
dspace.entity.typePublication
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Workflow_IEEEA_2020.pdf
Size:
1.23 MB
Format:
Adobe Portable Document Format
Download
Collections
DBIAB - BIIG - Journal Articles