Moreta Martínez, RafaelGarcía Mato, DavidGarcía Sevilla, MónicaPérez-Mañanes, RubénCalvo-Haro, JoséPascau González-Garzón, Javier2021-06-072021-06-072018-10Healthcare technology letters, 5(5) (Special Issue: Papers from the 12th workshop on Augmented Environments for Computer-Assisted Interventions, Granada, Spain, September 16th), Oct. 2018, Pp. 162-1662053-3713https://hdl.handle.net/10016/32842Proceeding of: 12th workshop on Augmented Environments for Computer-Assisted Interventions AE-CAI 2018, held in conjunction with MICCAI 2018, in Granada, Spain on September 16th.Augmented reality (AR) can be an interesting technology for clinical scenarios as an alternative to conventional surgical navigation. However, the registration between augmented data and real-world spaces is a limiting factor. In this study, the authors propose a method based on desktop three-dimensional (3D) printing to create patient-specific tools containing a visual pattern that enables automatic registration. This specific tool fits on the patient only in the location it was designed for, avoiding placement errors. This solution has been developed as a software application running on Microsoft HoloLens. The workflow was validated on a 3D printed phantom replicating the anatomy of a patient presenting an extraosseous Ewing's sarcoma, and then tested during the actual surgical intervention. The application allowed physicians to visualise the skin, bone and tumour location overlaid on the phantom and patient. This workflow could be extended to many clinical applications in the surgical field and also for training and simulation, in cases where hard body structures are involved. Although the authors have tested their workflow on AR head mounted display, they believe that a similar approach can be applied to other devices such as tablets or smartphones.5engThis is an open access article published by the IET under the Creative Commons Attribution-NonCommercial-NoDerivs License.Atribución-NoComercial-SinDerivadas 3.0 EspañaCancerAugmented realityTumoursComputerised tomographyMedical image processingSurgeryBoneImage registrationPaediatricsAugmented realityComputer-assisted interventionsPatient-specific 3D printed referenceReal-world spacesPatient-specific toolsVisual patternAutomatic registrationPlacement errorsSoftware applicationActual surgical interventionTumour locationSurgical fieldExtraosseous Ewing sarcomAugmented reality in computer-assisted interventions based on patient-specific 3D printed referenceeferenceconference paperBiología y Biomedicinahttps://doi.org/10.1049/htl.2018.5072open access1625166Healthcare technology letters (Special Issue: Papers from the 12th workshop on Augmented Environments for Computer-Assisted Interventions, Granada, Spain, September 16th)5CC/0000032482