Cal González, JacoboVaquero López, Juan JoséHerraiz, Joaquín L.Pérez Liva, MailynSoto Montenegro, Mª LuisaPeña Zalbidea, SantiagoDesco Menéndez, ManuelUdias Moinelo, José Manuel2022-11-162022-11-162018-08-01Cal-Gonzalez, J., Vaquero, J.J., Herraiz, J.L. et al. Improving PET Quantification of Small Animal [68Ga]DOTA-Labeled PET/CT Studies by Using a CT-Based Positron Range Correction. Mol Imaging Biol 20, 584–593 (2018)1536-16321860-2002 (electronic)https://hdl.handle.net/10016/36022Image quality of positron emission tomography (PET) tracers that emits high-energy positrons, such as Ga-68, Rb-82, or I-124, is significantly affected by positron range (PR) effects. PR effects are especially important in small animal PET studies, since they can limit spatial resolution and quantitative accuracy of the images. Since generators accessibility has made Ga-68 tracers wide available, the aim of this study is to show how the quantitative results of [Ga-68]DOTA-labeled PET/X-ray computed tomography (CT) imaging of neuroendocrine tumors in mice can be improved using positron range correction (PRC).10eng© The Authors, 2018This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.Atribución 3.0 EspañaEmission tomographyPreclinical evaluationMathematical removalSpatial resolutionMagnetic fieldShine throughImage quality3d petReconstructionSystemresearch articleBiología y Biomedicinahttps://doi.org/10.1007/s11307-018-1161-7open access584593Molecular Imaging and Biology20AR/0000023905