RT Journal Article
T1 Effect of hydrophobic interactions on lower critical solution temperature for poly(N-isopropylacrylamide-co-dopamine methacrylamide) copolymers
A1 García Peñas, Alberto
A1 Sekhar Biswas, Chandra
A1 Liang, Weijun
A1 Wang, Yu
A1 Yang, Pianpian
A1 Stadler, Florian J.
AB For the preparation of thermoresponsive copolymers, for e.g., tissue engineering scaffolds or drug carriers, a precise control of the synthesis parameters to set the lower critical solution temperature (LCST) is required. However, the correlations between molecular parameters and LCST are partially unknown and, furthermore, LCST is defined as an exact temperature, which oversimplifies the real situation. Here, random N-isopropylacrylamide (NIPAM)/dopamine methacrylamide (DMA) copolymers were prepared under a systematical variation of molecular weight and comonomer amount and their LCST in water studied by calorimetry, turbidimetry, and rheology. Structural information was deduced from observed transitions clarifying the contributions of molecular weight, comonomer content, end-group effect or polymerization degree on LCST, which were then statistically modeled. This proved that the LCST can be predicted through molecular structure and conditions of the solutions. While the hydrophobic DMA lowers the LCST especially the onset, polymerization degree has an important but smaller influence over all the whole LCST range.
PB MDPI
SN 2073-4360
YR 2019
FD 2019-06-04
LK https://hdl.handle.net/10016/38245
UL https://hdl.handle.net/10016/38245
LA eng
NO This research was funded by Shenzhen Fundamental Research Funds number KC2014ZDZJ0001A, the Shenzhen Sci & Tech research grant number ZDSYS201507141105130, and the China Postdoctoral Science Foundation Grant number 2018M633119.
DS e-Archivo
RD 1 jul. 2024