RT Journal Article T1 Design and testing of an optical instrument for skin flap monitoring A1 Moreno Oyervides, Aldo Luis A1 Diaz Ojeda, Luis A1 Bonilla Manrique, Óscar Elías A1 Bonastre-Julia, Jorge A1 Largo Aramburu, Carlota A1 Acedo Gallardo, Pablo A1 Martín Mateos, Pedro AB Flap procedures are complex surgical tools widely used in reconstructive surgery. Flap ischemia is one of the most dangerous complications, both during the surgical procedure and during the patient's recovery, which can quickly lead to tissue necrosis (flap loss) with serious medical and psychological consequences. Today, bedside clinical assessment remains the gold standard for flap monitoring, but timely detection of flap ischemia is a difficult and challenging task, so auxiliary techniques are needed to support flap monitoring. Here we present a prototype of a new optical diagnostic tool, based on visible light absorption in diffuse reflectance spectroscopy, for non-invasive, continuous, real-time monitoring of flaps. The proposed approach is assessed by monitoring flap ischemic scenarios induced on pig animal models. The results obtained support that the proposed approach has great potential, not only for prompt detection of ischemia (in seconds), but also for clear differentiation between an arterial occlusion and venous occlusion. PB Scientific Report SN 2045-2322 YR 2023 FD 2023-10-05 LK https://hdl.handle.net/10016/39589 UL https://hdl.handle.net/10016/39589 LA eng NO Funding. This work was supported by the Instituto de Salud Carlos III (Spain) under Grant DTS19/00146. DS e-Archivo RD 1 jul. 2024