RT Journal Article
T1 Study of CT-based positron range correction in high resolution 3D PET imaging
A1 Cal González, Jacobo
A1 Herraiz, J. L.
A1 España, Samuel
A1 Vicente, Esther
A1 Herranz, Elena
A1 Desco Menéndez, Manuel
A1 Vaquero López, Juan José
A1 Udías, José Manuel
AB Positron range limits the spatial resolution of PET images and has a different effect for different isotopesand positron propagationmaterials. Therefore it is important to consider it during image reconstruction,in order to obtain optimal image quality. Positron range distributions for most common isotopes used inPET in different materials were computed using the Monte Carlo simulations with PeneloPET. The rangeprofiles were introduced into the 3D OSEM image reconstruction software FIRST and employed to blur theimage either in the forward projection or in the forward and backward projection. The blurring introducedtakes into account the different materials in which the positron propagates. Information on thesematerials may be obtained, for instance, from a segmentation of a CT image. The results of introducingpositron blurring in both forward and backward projection operations was compared to using it onlyduring forward projection. Further, the effect of different shapes of positron range profile in the quality ofthe reconstructed images with positron range correction was studied. For high positron energy isotopes,the reconstructed images show significant improvement in spatial resolution when positron range istaken into account during reconstruction, compared to reconstructions without positron range modeling.
PB Elsevier
SN 0168-9002
YR 2011
FD 2011-08-21
LK http://hdl.handle.net/10016/14691
UL http://hdl.handle.net/10016/14691
LA eng
NO This work has been supported by the MEC (FPA2007 62216), the UCM (Grupos UCM, 910059), the CPAN (Consolider Ingenio 2010) CSPD 2007 00042, the RECAVA RETIC network, ARTEMIS S2009/ DPI 1802, the European Regional Development and ENTEPRASE grant, PSE 300000 2009 5 and the Ministerio de Ciencia e Innovación, Spanish Government.
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