RT Journal Article
T1 Effect of influenza-induced fever on human bioimpedance values
A1 Marini, Elisabetta
A1 Buffa, Roberto
A1 Contreras, Monica
A1 Magris, Magda
A1 Hidalgo, Glida
A1 Sánchez, Wilmer
A1 Ortiz, Vanessa
A1 Urbaez, Maryluz
A1 Cabras, Stefano
A1 Blaser, Martín J.
A1 Domínguez Bello, María G.
AB Background and AimsBioelectrical impedance analysis (BIA) is a widely used technique to assess body compositionand nutritional status. While bioelectrical values are affected by diverse variables, therehas been little research on validation of BIA in acute illness, especially to understand prognosticsignificance. Here we report the use of BIA in acute febrile states inducedby influenza.MethodsBioimpedance studies were conducted during an H1N1 influenza A outbreak in VenezuelanAmerindian villages from the Amazonas. Measurements were performed on 52 subjects between1 and 40 years of age, and 7 children were re-examined after starting Oseltamivirtreatment. Bioelectrical Impedance Vector Analysis (BIVA) and permutation testswere applied.ResultsFor the entire sample, febrile individuals showed a tendency toward greater reactance(p=0.058) and phase angle (p=0.037) than afebrile individuals, while resistance and impedancewere similar in the two groups. Individuals with repeated measurements showed significantdifferences in bioimpedance values associated with fever, including increasedreactance (p<0.001) and phase angle (p=0.007), and decreased resistance (p=0.007) andimpedance (p<0.001).ConclusionsThere are bioelectrical variations induced by influenza that can be related to dehydration,with lower extracellular to intracellular water ratio in febrile individuals, or a direct thermal effect.Caution is recommended when interpreting bioimpedance results in febrile states.
PB Public Library of Science
SN 1932-6203
YR 2015
FD 2015-04-27
LK https://hdl.handle.net/10016/35233
UL https://hdl.handle.net/10016/35233
LA eng
NO The study was partially supported by theC&D and Emch Research Funds and visitingProfessor program of University of Cagliari (toMGDB) and by the Diane Belfer Program for HumanMicrobial Ecology.
DS e-Archivo
RD 1 sept. 2024