RT Journal Article
T1 Modelling disorder: the cases of wetting and DNA denaturation
A1 Ares, Saúl
A1 Sánchez, Angel
AB We study the effect of the composition of the genetic sequence on the melting temperature ofdouble stranded DNA, using some simple analytically solvable models proposed in the framework of thewetting problem. We review previous work on disordered versions of these models and solve them whenthere were not preexistent solutions. We check the solutions with Monte Carlo simulations and transfermatrix numerical calculations. We present numerical evidence that suggests that the logarithmic correctionsto the critical temperature due to disorder, previously found in RSOS models, apply more generally toASOS and continuous models. The agreement between the theoretical models and experimental data showsthat, in this context, disorder should be the crucial ingredient of any model while other aspects may be keptvery simple, an approach that can be useful for a wider class of problems. Our work has also implicationsfor the existence of correlations in DNA sequences.
PB Springer
SN 434-6028 (print version)
SN 1434-6036 (online version)
YR 2007
FD 2007
LK https://hdl.handle.net/10016/14961
UL https://hdl.handle.net/10016/14961
LA eng
NO This work has been supported by the Ministerio de Ciencia y TecnologÍa of Spain through grants MOSAICO and NAN2004- 09087-C03-03 and Ingenio Mathematica (i-MATH) (AS) and by Comunidad de Madrid grant SIMUMAT-CM (AS).
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RD 1 sept. 2024