RT Conference Proceedings T1 Improved image reconstruction in small animal PET using a priori estimation of single-pixel events A1 España, Samuel A1 Herraiz, J. L. A1 Vicente, Esther A1 Herranz, Elena A1 Vaquero López, Juan José A1 Desco Menéndez, Manuel A1 Udías, José Manuel AB Most small animal PET scanners are based onarrays of pixelated scintillators crystals. As the read-out of individual pixels would be too expensive, identification of thecrystal of interaction is usually made by center of energy methods based for instance on Anger logic. This allows for a reduction in the number of signals to be acquired, but prevents the identification of multi-hit events, that is, events in that one (orseveral) photon produces several hits in the detector, thus blurring the correct positioning of the interaction. Improving theidentification of the pixel of interaction is pursued in this work by combining all the information acquired by the scanner withoutincreasing the number of signals. The probability for every individual event for being single or multi-pixel is estimated fromthe XY positioning and energy information. This probability is fed into a 3D-OSEM iterative statistical reconstruction method.Every coincidence event detected may be analyzed combining information such as deposited energy, PMT XY location, timedifference between both singles of the coincidence and coincidence and single rates, if available. With the proposedmethod, improved peak/noise ratio and better resolution are obtained without the introduction of additional hardware. PB IEEE SN 978-1-4244-0922-8 SN 1082-3654 YR 2007 FD 2007 LK https://hdl.handle.net/10016/12232 UL https://hdl.handle.net/10016/12232 LA eng NO Proceeding of: 2007 IEEE Nuclear Science Symposium Conference Record (NSS '07), Honolulu, Hawaii, USA, Oct. 27 - Nov. 3, 2007 NO This work has been partially funded by projects TEC2004-07052-C02 of Ministerio de Educación y Ciencia and CDTEAM, program CENIT, Ministerio de Industria, Spain. DS e-Archivo RD 3 may. 2024