RT Journal Article
T1 Dynamical community structure of populations evolving on genotype networks
A1 Capitán, José A.
A1 Aguirre, Jacobo
A1 Manrubia, Susanna C.
AB Neutral evolutionary dynamics of replicators occurs on large and heterogeneous networks of genotypes. These networks, formed by all genotypes that yield the same phenotype, have a complex architecture that conditions the molecular composition of populations and their movements on genome spaces. Here we consider as an example the case of populations evolving on RNA secondary structure neutral networks and study the community structure of the network revealed through dynamical properties of the population at equilibrium and during adaptive transients. We unveil a rich hierarchical community structure that, eventually, can be traced back to the non-trivial relationship between RNA secondary structure and sequence composition. We demonstrate that usual measures of modularity that only take into account the static, topological structure of networks, cannot identify the community structure disclosed by population dynamics.
PB Elsevier
SN 0960-0779
YR 2015
FD 2015-03
LK https://hdl.handle.net/10016/21463
UL https://hdl.handle.net/10016/21463
LA eng
NO This study has been supported by project FIS2011-27569 from the Spanish Ministry of Economy and Competitivity.
DS e-Archivo
RD 1 sept. 2024