RT Journal Article T1 The Impact of a Novel Immersive Virtual Reality Technology Associated with Serious Games in Parkinson's Disease Patients on Upper Limb Rehabilitation: A Mixed Methods Intervention Study A1 Sánchez-Herrera Baeza, Patricia A1 Cano de la Cuerda, Roberto A1 Oña Simbaña, Edwin Daniel A1 Palacios Ceña, Domingo A1 Perez Corrales, Jorge A1 Cuenca Zaldivar, Juan Nicolas A1 Gueita Rodriguez, Javier A1 Balaguer Bernaldo de Quirós, Carlos A1 Jardón Huete, Alberto A1 Cuesta Gomez, Alicia AB Parkinson’s disease is a neurodegenerative disorder that causes impairedmotor functions. Virtual reality technology may be recommended to optimize motor learning in asafe environment. The objective of this paper was to evaluate the e ects of a novel immersive virtualreality technology used for serious games (Oculus Rift 2 plus leap motion controller—OR2-LMC)for upper limb outcomes (muscle strength, coordination, speed of movements, fine and grossdexterity). Another objective was to obtain qualitative data for participants’ experiences related to theintervention. Methods: A mixed methods intervention (embedded) study was used, with a qualitativedesign after a technology intervention (quantitative design). The intervention and qualitative designfollowed international guidelines and were integrated into the method and reporting subheadings.Results: Significant improvements were observed in strength (p = 0.028), fine (p = 0.026 to 0.028) andgross coordination dexterity, and speed movements (p = 0.039) in the a ected side, with excellentcompliance (100%) and a high level of satisfaction (3.66 0.18 points out of the maximum of4). No adverse side e ects were observed. Qualitative findings described patients’ perspectivesregarding OR2-LMC treatment, facilitators and barriers for adherence, OR2-LMC applications,and treatment improvements. Conclusions: The intervention showed positive results for theupper limbs, with elements of discordance, expansion, and confirmation between qualitative andquantitative results. PB MDPI SN 1424-8220 YR 2020 FD 2020-04-11 LK https://hdl.handle.net/10016/33971 UL https://hdl.handle.net/10016/33971 LA eng DS e-Archivo RD 1 sept. 2024