A Novel Bayesian Linear Regression Model for the Analysis of Neuroimaging Data
Publisher:
MDPI AG
Issued date:
2022-03-01
Citation:
Belenguer-Llorens, A., Sevilla-Salcedo, C., Desco, M., Soto-Montenegro, M. L., & Gómez-Verdejo, V. (2022). A Novel Bayesian Linear Regression Model for the Analysis of Neuroimaging Data. In Applied Sciences, 12(5), 2571-2588
ISSN:
1454-5101
xmlui.dri2xhtml.METS-1.0.item-contributor-funder:
Comunidad de Madrid
European Commission
Ministerio de Ciencia, Innovación y Universidades (España)
Universidad Carlos III de Madrid
Sponsor:
This paper is part of the project PID2020-115363RB-I00 funded by MCIN/AEI/10.13039/
501100011033. A.B.-L.’s work is funded by the Community of Madrid through the “Excellence of
University Teaching Staff” line of the Multi-year Agreement with UC3M (EPUC3M27), within the
framework of the V PRICIT. M.L.S.-M.’s was supported by Ministerio de Ciencia, Innovación y Universidades,
Instituto de Salud Carlos III (project number PI17/01766, and grant number BA21/00030),
co-financed by European Regional Development Fund (ERDF), “A way to make Europe”, CIBER
de Salud Mental (project number CB07/09/0031), Delegación del Gobierno para el Plan Nacional
sobre Drogas (project number 2017/085); Fundación Mapfre and Fundación Alicia Koplowitz. M.D.’s
work was supported by Ministerio de Ciencia e Innovación (MCIN) and Instituto de Salud Carlos III
(ISCIII) (PT20/00044). The CNIC is supported by the ISCIII, the MCIN and the Pro CNIC Foundation,
and is a Severo Ochoa Center of Excellence (SEV-2015-0505).
Project:
Gobierno de España. PID2020-115363RB-I00
Comunidad de Madrid. EPUC3M27
Gobierno de España. BA21/00030
Gobierno de España. PT20/00044
Gobierno de España. SEV-2015-0505
Keywords:
Bayesian learning
,
Neuroimaging
,
Feature selection
,
Kernel formulation
,
Mental disorders
,
Schizophrenia
,
Mri
Rights:
© 2022 by the authors.
Licensee MDPI, Basel, Switzerland.
Atribución 3.0 España
Abstract:
In this paper, we propose a novel Machine Learning Model based on Bayesian Linear
Regression intended to deal with the low sample-to-variable ratio typically found in neuroimaging
studies and focusing on mental disorders. The proposed model combines feature
In this paper, we propose a novel Machine Learning Model based on Bayesian Linear
Regression intended to deal with the low sample-to-variable ratio typically found in neuroimaging
studies and focusing on mental disorders. The proposed model combines feature selection capabilities
with a formulation in the dual space which, in turn, enables efficient work with neuroimaging
data. Thus, we have tested the proposed algorithm with real MRI data from an animal model of
schizophrenia. The results show that our proposal efficiently predicts the diagnosis and, at the same
time, detects regions which clearly match brain areas well-known to be related to schizophrenia.
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