Alcohol use disorders and associated chronic disease - A national retrospective cohort study from France

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Show simple item record Thiebaut, Sophie Schwarzinger, Michaël Baillot, Sylvain Mallet, Vincent Rehm, Jürgen 2022-04-05T13:55:16Z 2022-04-05T13:55:16Z 2017-07
dc.identifier.bibliographicCitation Schwarzinger, M., Thiébaut, S. P., Baillot, S., Mallet, V., & Rehm, J. (2017). Alcohol use disorders and associated chronic disease – a national retrospective cohort study from France. BMC Public Health, 18 (1).
dc.identifier.issn 1471-2458
dc.description.abstract Background: Evidence on diseases caused by or associated with alcohol use disorders (AUDs) has been based on two meta-analyses including rather dated studies. The objective of this contribution was to estimate the risks of all-cause mortality and alcohol-attributable disease categories depending on a diagnosis of AUDs in a national sample for France. Methods: In a national retrospective cohort study on all inpatient acute and rehabilitation care patients in Metropolitan France 2008–2012 (N = 26,356,361), AUDs and other disease categories were identified from all discharge diagnoses according to standard definitions, and we relied on in-hospital death for mortality (57.4% of all deaths). Results: 704,803 (2.7%) patients identified with AUDs had a threefold higher risk of death (HR = 2.98; 95% CI: 2.96–3. 00) and died on average 12.2 years younger (men: 10.4, 95% CI: 10.3–10.5; women: 13.7, 95% CI: 13.6–13.9). AUDs were associated with significantly higher risks of hospital admission for all alcohol-attributable disease categories: digestive diseases, cancers (exception: breast cancer), cardiovascular diseases, dementia, infectious diseases, and injuries. Elevated risks were highest for liver diseases that were associated with about two-third of deaths in patients with AUDs (men: 64.3%; women: 71.1%). Conclusions: AUDs were associated with marked premature mortality and higher risks of alcohol-attributable disease categories. Our results support the urgent need of measures to reduce the burden of AUDs.
dc.language.iso eng
dc.publisher BMC
dc.rights © The Author(s).
dc.rights Atribución 3.0 España
dc.subject.other Alcohol use disorders
dc.subject.other Burden of disease
dc.subject.other Mortality
dc.subject.other Non-communicable disease
dc.subject.other Risk factor
dc.title Alcohol use disorders and associated chronic disease - A national retrospective cohort study from France
dc.type article
dc.subject.eciencia Economía
dc.rights.accessRights openAccess
dc.type.version publishedVersion
dc.identifier.publicationfirstpage 1
dc.identifier.publicationissue 1
dc.identifier.publicationlastpage 9
dc.identifier.publicationtitle BMC Public Health (BMC Public Health)
dc.identifier.publicationvolume 18
dc.identifier.uxxi AR/0000029483
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