Craniosynostosis surgery: workflow based on virtual surgical planning, intraoperative navigation and 3D printed patient-specific guides and templates

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dc.contributor.author García Mato, David
dc.contributor.author Ochandiano, Santiago
dc.contributor.author García Sevilla, Mónica
dc.contributor.author Navarro-Cuéllar, Carlos
dc.contributor.author Darriba-Alles, Juan V.
dc.contributor.author García Leal, Roberto
dc.contributor.author Calvo-Haro, José A.
dc.contributor.author Pérez-Mañanes, Rubén
dc.contributor.author Salmerón, José I.
dc.contributor.author Pascau González-Garzón, Javier
dc.date.accessioned 2021-02-12T12:16:30Z
dc.date.available 2021-02-12T12:16:30Z
dc.date.issued 2019-12-01
dc.identifier.bibliographicCitation García-Mato, D., Ochandiano, S., García-Sevilla, M. et al. Craniosynostosis surgery: workflow based on virtual surgical planning, intraoperative navigation and 3D printed patient-specific guides and templates. Sci Rep 9, 17691 (2019)
dc.identifier.issn 2045-2322
dc.identifier.uri http://hdl.handle.net/10016/31919
dc.description.abstract Craniosynostosis must often be corrected using surgery, by which the affected bone tissue is remodeled. Nowadays, surgical reconstruction relies mostly on the subjective judgement of the surgeon to best restore normal skull shape, since remodeled bone is manually placed and fixed. Slight variations can compromise the cosmetic outcome. The objective of this study was to describe and evaluate a novel workflow for patient-specific correction of craniosynostosis based on intraoperative navigation and 3D printing. The workflow was followed in five patients with craniosynostosis. Virtual surgical planning was performed, and patient-specific cutting guides and templates were designed and manufactured. These guides and templates were used to control osteotomies and bone remodeling. An intraoperative navigation system based on optical tracking made it possible to follow preoperative virtual planning in the operating room through real-time positioning and 3D visualization. Navigation accuracy was estimated using intraoperative surface scanning as the gold-standard. An average error of 0.62 mm and 0.64 mm was obtained in the remodeled frontal region and supraorbital bar, respectively. Intraoperative navigation is an accurate and reproducible technique for correction of craniosynostosis that enables optimal translation of the preoperative plan to the operating room. © 2019, The Author(s).
dc.description.sponsorship This work has been supported by Ministerio de Ciencia, Innovación y Universidades, Instituto de Salud Carlos III, project “PI18/01625”, co-funded by European Regional Development Fund (ERDF), “A way of making Europe”.
dc.language.iso eng
dc.publisher Nature
dc.rights © The Author(s) 2019
dc.rights Atribución 3.0 España
dc.rights.uri http://creativecommons.org/licenses/by/3.0/es/
dc.subject.other Craniosynostoses
dc.subject.other Skull
dc.subject.other Craniosynostosis surgery
dc.title Craniosynostosis surgery: workflow based on virtual surgical planning, intraoperative navigation and 3D printed patient-specific guides and templates
dc.type article
dc.subject.eciencia Biología y Biomedicina
dc.identifier.doi https://doi.org/10.1038/s41598-019-54148-4
dc.rights.accessRights openAccess
dc.relation.projectID Gobierno de España. PI18/01625
dc.type.version publishedVersion
dc.identifier.publicationissue 1
dc.identifier.publicationtitle Scientific Reports
dc.identifier.publicationvolume 9
dc.identifier.uxxi AR/0000024235
dc.contributor.funder Ministerio de Ciencia, Innovación y Universidades (España)
dc.affiliation.dpto UC3M. Departamento de Bioingeniería
dc.affiliation.grupoinv UC3M. Grupo de Investigación: Biomedical Imaging and Instrumentation Group
dc.affiliation.grupoinv UC3M. Grupo de Investigación: BSEL - Laboratorio de Ciencia e Ingeniería Biomédica
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