Conceptual models of drug-drug interactions: A summary of recent efforts

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dc.contributor.author Herrero Zazo, María
dc.contributor.author Segura-Bedmar, Isabel
dc.contributor.author Martínez Fernández, Paloma
dc.date.accessioned 2020-11-04T10:31:30Z
dc.date.available 2020-11-04T10:31:30Z
dc.date.issued 2016-12-15
dc.identifier.bibliographicCitation Herrero-Zazo, M., Segura-Bedmar, I., Martínez, P. (2016). Conceptual models of drug-drug interactions: A summary of recent efforts. Knowledge-Based Systems, 114, pp. 99-107.
dc.identifier.issn 0950-7051
dc.identifier.uri http://hdl.handle.net/10016/31332
dc.description.abstract Conceptual modeling elicits and describes general knowledge in a particular domain and is a fundamental step in the development of knowledge-based systems. However, different conceptual models (CMs) could represent the same domain because they result from human intellectual activity with different objectives. Analyzing previous related efforts is crucial when conceptualizing a domain to avoid duplication, increase interoperability and ensure scientific conformity. Our domain of interest is drug-drug interactions (DDIs), and here we review 15 studies that have attempted total or partial representation of the DDI domain. Direct comparison of these different conceptualizations is complex because CMs are usually not provided, differ considerably from each other or are described with diverse formalisms at different abstraction levels. Therefore, to compare these CMs, we represent all of them in a common representation framework.
dc.description.sponsorship This work was partially supported by eGovernAbility-Access project [TIN2014-52665-C2-2-R].
dc.language.iso eng
dc.publisher Elsevier
dc.rights © 2016 Elsevier B.V. All rights reserved.
dc.rights Atribución-NoComercial-SinDerivadas 3.0 España
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subject.other Drug-Drug interactions
dc.subject.other Conceptual modeling
dc.subject.other Knowledge representation
dc.subject.other Natural language processing
dc.subject.other Computational inference
dc.title Conceptual models of drug-drug interactions: A summary of recent efforts
dc.type article
dc.subject.eciencia Informática
dc.identifier.doi https://doi.org/10.1016/j.knosys.2016.10.006
dc.rights.accessRights openAccess
dc.relation.projectID Gobierno de España. TIN2014-52665-C2-2-R
dc.type.version acceptedVersion
dc.identifier.publicationfirstpage 99
dc.identifier.publicationlastpage 107
dc.identifier.publicationtitle KNOWLEDGE-BASED SYSTEMS
dc.identifier.publicationvolume 114
dc.identifier.uxxi AR/0000018552
dc.contributor.funder Ministerio de Economía y Competitividad (España)
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