On the mechanical behaviour of PEEK and HA cranial implants under impact loading

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dc.contributor.author García González, Daniel
dc.contributor.author Jayamohan, J.
dc.contributor.author Sotiropoulos, S. N.
dc.contributor.author Yoon, S.-H.
dc.contributor.author Cook, J.
dc.contributor.author Siviour, C. R.
dc.contributor.author Arias Hernández, Ángel
dc.contributor.author Jerusalem, A.
dc.date.accessioned 2018-07-04T12:24:47Z
dc.date.available 2018-07-04T12:24:47Z
dc.date.issued 2017-05
dc.identifier.bibliographicCitation Journal of the Mechanical Behavior of Biomedical Materials, 69, pp. 342-354
dc.identifier.issn 1751-6161
dc.identifier.uri http://hdl.handle.net/10016/27132
dc.description.abstract The human head can be subjected to numerous impact loadings such as those produced by a fall or during sport activities. These accidents can result in skull fracture and in some complex cases, part of the skull may need to be replaced by a biomedical implant. Even when the skull is not damaged, such accidents can result in brain swelling treated by decompressive craniectomy. Usually, after recovery, the part of the skull that has been removed is replaced by a prosthesis. In such situations, a computational tool able to analyse the choice of prosthesis material depending on the patient's specific activity has the potential to be extremely useful for clinicians. The work proposed here focusses on the development and use of a numerical model for the analysis of cranial implants under impact conditions. In particular, two main biomaterials commonly employed for this kind of prosthesis are polyether-ether-ketone (PEEK) and macroporous hydroxyapatite (HA). In order to study the suitability of these implants, a finite element head model comprising scalp, skull, cerebral falx, cerebrospinal fluid and brain tissues, with a cranial implant replacing part of the skull has been developed from magnetic resonance imaging data. The human tissues and these two biocompatible materials have been independently studied and their constitutive models are provided here. A computational model of the human head under impact loading is then implemented and validated, and a numerical comparison of the mechanical impact response of PEEK and HA implants is presented. This comparison was carried out in terms of the effectiveness of both implants in ensuring structural integrity and preventing traumatic brain injury.
dc.description.sponsorship The researchers of the University Carlos III are indebted to the Ministerio de Economía y Competitividad de España (Project DPI2014-57989-P) and Vicerrectorado de Política Científica UC3M (Project 2013-00219-002) for the financial support. A.J. acknowledges funding from the European Union's Seventh Framework Programme (FP7 2007–2013) ERC Grant Agreement No. 306587. MRI data were provided by the Human Connectome Project, WUMinn Consortium (Principal Investigators: David Van Essen and Kamil Ugurbil; 1U54MH091657) funded by the 16 NIH Institutes and Centers that support the NIH Blueprint for Neuroscience Research; and by the McDonnell Center for Systems Neuroscience at Washington University. Finally, we would like to thank Dr. S Barhli and Prof. J Marrow for valuable assistance with the X-ray tomography; the machine used was bought from EPSRC Grant EP/M02833X/1 “University of Oxford: experimental equipment upgrade”. Open Access funded by European Research Council
dc.format.extent 13
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Elsevier Ltd.
dc.rights © 2017 The Authors. This is an open access article under the CC BY-NC-ND license
dc.rights Atribución-NoComercial-SinDerivadas 3.0 España
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.subject.other Finite element head model
dc.subject.other Cranial implant
dc.subject.other PEEK
dc.subject.other Macroporous HA
dc.subject.other Impact loading
dc.title On the mechanical behaviour of PEEK and HA cranial implants under impact loading
dc.type article
dc.subject.eciencia Biología y Biomedicina
dc.subject.eciencia Ingeniería Mecánica
dc.identifier.doi https://doi.org/10.1016/j.jmbbm.2017.01.012
dc.rights.accessRights openAccess
dc.relation.projectID Gobierno de España. DPI2014-57989-P
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/306587
dc.type.version publishedVersion
dc.identifier.publicationfirstpage 342
dc.identifier.publicationlastpage 354
dc.identifier.publicationtitle Journal of the Mechanical Behavior of Biomedical Materials
dc.identifier.publicationvolume 69
dc.identifier.uxxi AR/0000020029
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