Deadtime and pile-up correction method based on the singles to coincidences ratio for PET

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dc.contributor.author Herraiz, J. L.
dc.contributor.author España, Samuel
dc.contributor.author Herranz, E.
dc.contributor.author Desco Menéndez, Manuel
dc.contributor.author Vaquero López, Juan José
dc.contributor.author Udías, José Manuel
dc.contributor.author Vicente, Esther
dc.date.accessioned 2015-03-03T09:41:14Z
dc.date.available 2015-03-03T09:41:14Z
dc.date.issued 2011
dc.identifier.bibliographicCitation 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC): Valencia, Spain. 23-29 October 2011 (2011). IEEE, 2933-2935.
dc.identifier.isbn 978-1-4673-0118-3
dc.identifier.issn 1082-3654
dc.identifier.uri http://hdl.handle.net/10016/20129
dc.description Proceedings of: 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC). Valencia, Spain, 23-29 October 2011
dc.description.abstract he count rate in a PET scanner as a function of the activity in the Field of View (FOV) has a non-linear contribution coming from deadtime, pile-up and random coincidences. These effects must be estimated accurately and corrected in order to perform quantitative PET studies. For a given scanner and acquisition system, the relative importance of deadtime and pile-up effects still depends on the size and materials of the objects being imaged. These facts difficult to devise a universal correction method that yields accurate results for any kind of acquisition. In this work we show that, in a PET scanner, there is a linear relationship between the effective deadtime for coincidences, tau, (which takes into account deadtime and pile-up losses and gains within the energy window) and the Singles to Coincidences Ratio (SCRm) measured by the scanner. This relation has been recovered both in simulations and real data. This allows us to devise a simple method which, requiring only two calibration acquisitions for each energy window, one with high SCRm and one with low SCRm, is able to estimate accurately deadtime and pile up corrections for any other acquisition performed in the same scanner. Simulations show that corrected count rates are accurate within 5%, even when high activities are present in the FOV.
dc.description.sponsorship This work was supported from Comunidad de Madrid (ARTEMIS S2009/DPI 1802), Spanish Ministry of Science and Innovation (ENTEPRASE Grant, PSE 300000 2009 5) and PRECISION grant IPT 300000 2010 3, UCM (Grupos UCM, 910059), and european regional funds and CPAN, Centro de Fisica de Particulas, Astroparticulas y Nuclear (CSD 2007 00042@lngenio2010 12). This study has been (partially) funded by CDTI under the CENIT Programme (AMIT Project). Part of the calculations of this work was performed in the "Cluster de Calculo de Alta Capacidad para Tecnicas Fisicas" funded in part by UCM and in part by UE with European regional funds".
dc.format.extent 3
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher Ieee - The Institute Of Electrical And Electronics Engineers, Inc
dc.rights © 2011 IEEE.
dc.subject.other Data acquisition
dc.subject.other Positron emission tomography
dc.title Deadtime and pile-up correction method based on the singles to coincidences ratio for PET
dc.type conferenceObject
dc.type bookPart
dc.description.status Publicado
dc.relation.publisherversion http://dx.doi.org/10.1109/NSSMIC.2011.6152523
dc.subject.eciencia Biología y Biomedicina
dc.subject.eciencia Medicina
dc.identifier.doi 10.1109/NSSMIC.2011.6152523
dc.rights.accessRights openAccess
dc.relation.projectID Comunidad de Madrid. S2009/DPI-1802/ARTEMIS
dc.relation.projectID Gobierno de España. PSE-300000-2009-5
dc.relation.projectID Gobierno de España. PT-300000-2010-3
dc.type.version acceptedVersion
dc.relation.eventdate 23-29 October 2011
dc.relation.eventplace Valencia, España.
dc.relation.eventtitle 2011 IEEE Nuclear Science Symposiun and Medical Imaging Conference (NSS-MIC)
dc.relation.eventtype proceeding
dc.identifier.publicationfirstpage 2933
dc.identifier.publicationlastpage 2935
dc.identifier.publicationtitle 2011 IEEE Nuclear Science Symposiun and Medical Imaging Conference (NSS-MIC)
dc.identifier.uxxi CC/0000016114
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