Initial results from a PET/planar small animal imaging system

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Show simple item record Siegel, Stefan Vaquero López, Juan José Aloj, L. Seidel, Jürgen Jagoda, E. Gandler, William R. Eckelman, William C. Green, Michael V. 2012-06-14T10:04:01Z 2012-06-14T10:04:01Z 1999-06
dc.identifier.bibliographicCitation IEEE Transactions on Nuclear Science, vol. 46, n. 3, jun. 1999. Pp. 571-575
dc.identifier.issn 0018-9499
dc.description.abstract A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positronemitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. The system uses FERA (LeCroy Research Systems) charge-sensitive ADCs and a low cost digital YO board as a E R A bus-to-host bridge. In projection mode, the animal is placed within the 55 mm x 45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from those lines falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of slowly varying tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically engineered mice.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher IEEE
dc.rights © IEEE
dc.title Initial results from a PET/planar small animal imaging system
dc.type article
dc.description.status Publicado
dc.subject.eciencia Biología y Biomedicina
dc.identifier.doi 10.1109/23.775581
dc.rights.accessRights openAccess
dc.type.version acceptedVersion
dc.identifier.publicationfirstpage 571
dc.identifier.publicationissue n. 3
dc.identifier.publicationlastpage 575
dc.identifier.publicationtitle IEEE Transactions on Nuclear Science
dc.identifier.publicationvolume vol. 46
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