Improved image reconstruction in small animal PET using a priori estimation of single-pixel events

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dc.contributor.author España, Samuel
dc.contributor.author Herraiz, J. L.
dc.contributor.author Vicente, Esther
dc.contributor.author Herranz, Elena
dc.contributor.author Vaquero López, Juan José
dc.contributor.author Desco Menéndez, Manuel
dc.contributor.author Udías, José Manuel
dc.date.accessioned 2011-10-05T13:44:01Z
dc.date.available 2011-10-05T13:44:01Z
dc.date.issued 2007
dc.identifier.bibliographicCitation 2007 IEEE Nuclear Science Symposium Conference Record, 2007, vol. 5, p. 3876 - 3880
dc.identifier.isbn 978-1-4244-0922-8
dc.identifier.issn 1082-3654
dc.identifier.uri http://hdl.handle.net/10016/12232
dc.description Proceeding of: 2007 IEEE Nuclear Science Symposium Conference Record (NSS '07), Honolulu, Hawaii, USA, Oct. 27 - Nov. 3, 2007
dc.description.abstract Most small animal PET scanners are based on arrays of pixelated scintillators crystals. As the read-out of individual pixels would be too expensive, identification of the crystal of interaction is usually made by center of energy methods based for instance on Anger logic. This allows for a reduction in the number of signals to be acquired, but prevents the identification of multi-hit events, that is, events in that one (or several) photon produces several hits in the detector, thus blurring the correct positioning of the interaction. Improving the identification of the pixel of interaction is pursued in this work by combining all the information acquired by the scanner without increasing the number of signals. The probability for every individual event for being single or multi-pixel is estimated from the XY positioning and energy information. This probability is fed into a 3D-OSEM iterative statistical reconstruction method. Every coincidence event detected may be analyzed combining information such as deposited energy, PMT XY location, time difference between both singles of the coincidence and coincidence and single rates, if available. With the proposed method, improved peak/noise ratio and better resolution are obtained without the introduction of additional hardware.
dc.description.sponsorship This work has been partially funded by projects TEC2004-07052-C02 of Ministerio de Educación y Ciencia and CDTEAM, program CENIT, Ministerio de Industria, Spain.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher IEEE
dc.rights © IEEE
dc.title Improved image reconstruction in small animal PET using a priori estimation of single-pixel events
dc.type bookPart
dc.type conferenceObject
dc.relation.publisherversion http://dx.doi.org/10.1109/NSSMIC.2007.4436965
dc.subject.eciencia Biología y Biomedicina
dc.identifier.doi 10.1109/NSSMIC.2007.4436965
dc.rights.accessRights openAccess
dc.relation.eventdate Oct. 27 - Nov. 3, 2007
dc.relation.eventplace Honolulu, Hawaii, USA
dc.relation.eventtitle 2007 IEEE Nuclear Science Symposium Conference Record (NSS '07)
dc.identifier.publicationfirstpage 3876
dc.identifier.publicationlastpage 3880
dc.identifier.publicationtitle 2007 IEEE Nuclear Science Symposium Conference Record
dc.identifier.publicationvolume 5
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