Resolution uniformity and sensitivity of the NIH ATLAS small animal PET scanner: comparison to simulated LSO scanners without depth-of-interaction capability

Repositorio e-Archivo

Mostrar el registro sencillo del ítem

dc.contributor.author Seidel, Jürgen
dc.contributor.author Vaquero López, Juan José
dc.contributor.author Green, Michael V.
dc.date.accessioned 2011-09-19T12:51:41Z
dc.date.available 2011-09-19T12:51:41Z
dc.date.issued 2001
dc.identifier.bibliographicCitation 2001 IEEE Nuclear Science Symposium Conference Record, 2001, n. 3, p. 1555-1558
dc.identifier.isbn 0-7803-7324-3
dc.identifier.issn 1082-3654
dc.identifier.uri http://hdl.handle.net/10016/12110
dc.description Proceeding of: 2001 Nuclear Science Symposium and Medical Imaging Conference, november 4-10, 2001, San Diego, California
dc.description.abstract PET scanners designed to image animals the size of rats and mice should possess simultaneously high and uniform spatial resolution and high sensitivity. ATLAS (Advanced Technology Laboratory Animal Scanner), an 11.8 cm diameter aperture, 2 cm axial field-of-view ring-type research scanner seeks these goals by surrounding the animal with eighteen 15 mm deep, LGSO (7 mm) / GSO (8 mm) phoswich detector modules. A Monte Carlo simulation was used to compare the variation of resolution across the field-of-view and the absolute central point source sensitivity (ACS) of ATLAS to similar systems comprised only of LSO arrays of different depths with no depth-of-interaction (DOI) capability. For ATLAS radial spatial resolution deteriorated by 27% from the center to 3 cm off-axis. Scanners comprised of 15 mm deep, 10 mm deep and 7 mm deep LSO crystals deteriorated by 100%, 51%, and 20% respectively, over the same distance. Simulated ACS (absorbed energies > 250 keV) for ATLAS was 2.0% and for the 15 mm, 10 mm deep and 7 mm deep LSO scanners 2.4%, 1.5%, and 0.9%, respectively. Radial resolution loss 3 cm off-axis and ACS measured for the actual ATLAS scanner were similar to the values obtained by simulation (27% resolution loss, 1.8% ACS). The phoswich design thus achieves good resolution uniformity over a 6 cm FOV while preserving sensitivity compared to equivalent non-DOI LSO scanners with a range of crystal depths.
dc.format.mimetype application/pdf
dc.language.iso eng
dc.publisher IEEE
dc.relation.hasversion http://e-archivo.uc3m.es/handle/10016/9358
dc.rights © IEEE
dc.title Resolution uniformity and sensitivity of the NIH ATLAS small animal PET scanner: comparison to simulated LSO scanners without depth-of-interaction capability
dc.type conferenceObject
dc.description.status Publicado
dc.relation.publisherversion http://dx.doi.org/10.1109/NSSMIC.2001.1008634
dc.subject.eciencia Biología y Biomedicina
dc.identifier.doi 10.1109/NSSMIC.2001.1008634
dc.rights.accessRights openAccess
dc.type.version acceptedVersion
dc.relation.eventdate November 4-10, 2001
dc.relation.eventplace San Diego, California
dc.relation.eventtitle 2001 Nuclear Science Symposium and Medical Imaging Conference
dc.relation.eventtype Proceeding
dc.identifier.publicationfirstpage 1555
dc.identifier.publicationissue 3
dc.identifier.publicationlastpage 1558
dc.identifier.publicationtitle 2001 IEEE Nuclear Science Symposium Conference Record
 Find Full text

Ficheros en el ítem

*Click en la imagen del fichero para previsualizar.(Los elementos embargados carecen de esta funcionalidad)


Este ítem aparece en la(s) siguiente(s) colección(es)

Mostrar el registro sencillo del ítem