Intranasal administration is one of the main routes of allergen challenge in mouse models of airway disease. Although it is widely used, it is not well established the amount of allergen that reaches the lung or is lost to the gastrointestinal tract. The localIntranasal administration is one of the main routes of allergen challenge in mouse models of airway disease. Although it is widely used, it is not well established the amount of allergen that reaches the lung or is lost to the gastrointestinal tract. The local distribution of the challenge solution within the airways is also unknown. The aim of this study was to assess the distribution immediately after intranasal delivery using a Positron Emission Tomography scanner (PET)[+][-]
Nota:
Abstract of: Scientific Sessions: 2007 AAAAI Annual Meeting, February 23-27, San Diego, CA
