Positron emission tomography of the airway distribution of intranasal challenge solutions

Conejero, Laura; Soto Montenegro, M. L.; Vaquero López, Juan José; Baeza, M. L.; Varela Nieto, I.; Desco Menéndez, Manuel; Zubeldia, José Manuel; Lage Negro, Eduardo

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Positron emission tomography of the airway distribution of intranasal challenge solutions

Author(s): Conejero, Laura; Soto Montenegro, M. L.; Vaquero López, Juan José; Baeza, M. L.; Varela Nieto, I.; Desco Menéndez, Manuel; Zubeldia, José Manuel; Lage Negro, Eduardo

Publisher: Elsevier

Issued date: 2007

Citation: Journal of Allergy and Clinical Immunology, enero 2007, vol. 119, n. 1, p. S306

ISSN: 0091-6749

DOI: 10.1016/j.jaci.2006.12.569

Sponsor: FIS 01/0598 and Foundation SEAIC

Publisher version: http://download.journals.elsevierhealth.com/pdfs/journals/0091-6749/PIIS0091674906037006.pdf
http://dx.doi.org/10.1016/j.jaci.2006.12.569

URI: http://hdl.handle.net/10016/11990

Rights: © Elsevier

Abstract:

Intranasal administration is one of the main routes of allergen challenge in mouse models of airway disease. Although it is widely used, it is not well established the amount of allergen that reaches the lung or is lost to the gastrointestinal tract. The local [+]