Publication:
Two mechanisms regulate directional cell growth in Arabidopsis lateral roots

dc.affiliation.dptoUC3M. Departamento de Economíaes
dc.contributor.authorGarcía González, Daniel
dc.date.accessioned2022-04-01T17:33:57Z
dc.date.available2022-04-01T17:33:57Z
dc.date.issued2019-01-01
dc.description.abstractMorphogenesis in plants depends critically on directional (anisotropic) growth. This occurs principally perpendicular to the net orientation of cellulose microfibrils (CMFs), which is in turn controlled by cortical microtubules (CMTs). In young lateral roots of Arabidopsis thaliana, growth anisotropy also depends on RAB-A5c, a plant-specific small GTPase that specifies a membrane trafficking pathway to the geometric edges of cells. Here we investigate the functional relationship between structural anisotropy at faces and RAB-A5c activity at edges during lateral root development. We show that surprisingly, inhibition of RAB-A5c function is associated with increased CMT/CMF anisotropy. We present genetic, pharmacological, and modelling evidence that this increase in CMT/CMF anisotropy partially compensates for loss of an independent RAB-A5c-mediated mechanism that maintains anisotropic growth in meristematic cells. We show that RAB-A5c associates with CMTs at cell edges, indicating that CMTs act as an integration point for both mechanisms controlling cellular growth anisotropy in lateral rootsen
dc.identifier.bibliographicCitationGoryakin, Y., Thiébaut, S. P., Cortaredona, S., Lerouge, M. A., Cecchini, M., Feigl, A. B., & Ventelou, B. (2020). Assessing the future medical cost burden for the European health systems under alternative exposure-to-risks scenarios. PLOS ONE, 15(9), p. e0238565es
dc.identifier.doihttps://doi.org/10.7554/eLife.47988
dc.identifier.issn2050-084X
dc.identifier.publicationfirstpage1es
dc.identifier.publicationissuee47988es
dc.identifier.publicationlastpage26es
dc.identifier.publicationtitleeLifees
dc.identifier.publicationvolume8es
dc.identifier.urihttps://hdl.handle.net/10016/34517
dc.identifier.uxxiAR/0000024984
dc.language.isoenges
dc.publisherPublic Library of Sciencees
dc.rights© 2020 Goryakin et al.es
dc.rightsAtribución-NoComercial 3.0 España*
dc.rights.accessRightsopen accesses
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/es/*
dc.titleTwo mechanisms regulate directional cell growth in Arabidopsis lateral rootses
dc.typeresearch article*
dc.type.hasVersionVoR*
dspace.entity.typePublication
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