Publication:
Programmed ventricular stimulation for predicting arrhythmic events in patients with myocardial infarction: a systematic review and meta-analysis

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Abstract
Left ventricular ejection fraction (LVEF) is at present the main parameter used to guide the implantation of cardioverter-defibrillators (ICD) in patients with ischaemic cardiomyopathy. However, LVEF alone is a poor predictor of ventricular arrhythmias (VA) and sudden cardiac death (SCD). The majority of ICDs implanted for the primary prevention of SCD never deliver appropriate therapies, while being an expensive therapy and being potentially iatrogenic. Therefore, insertion of ICDs based solely on LVEF is not efficient and calls for an improvement in the risk-stratification of post-myocardial infarction patients. Inducibility of ventricular arrhythmias with programmed ventricular stimulation (PVS) has been used in the past to assess the risk of malignant arrhythmias. However, its current role in clinical practice is unknown.
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Keywords
Cardiac arrhythmia, Myocardial infarction, Primary prevention, Left ventricular ejection fraction, Myocardial ischemia, Sudden cardiac death, Ventricular tachycardia, Monomorphic, Implantable defibrillators, Ischemic cardiomyopathy, Ventricular tachycardia, Induced, Heterogeneity, Follow-up, Infarction, Medline, Ventricular arrhythmia, Defibrillators, Post myocardial infarction, Visual analogue pain scale, Stratification, Cochrane collaboration, Embase, Primary outcome measure
Bibliographic citation
Carta Bergaz, A., Soto-Flores, N., Arenal-Maiz, A., Atienza-Fernandez, F., Gonzalez-Torrecilla, E., Gonzalez-Casal, D., Rios-Munoz, G., Perez-Espejo, P., Garcia-Montero, M., Fernandez-Aviles, F. & Avila-Alonso, P. (2022). Programmed ventricular stimulation for predicting arrhythmic events in patients with myocardial infarction: a systematic review and meta-analysis. EP Europace, 24(Supplement_1), i511-i512.