Publication:
Alcohol use disorders and associated chronic disease - A national retrospective cohort study from France

dc.affiliation.dptoUC3M. Departamento de Economíaes
dc.contributor.authorThiebaut, Sophie
dc.contributor.authorSchwarzinger, Michaël
dc.contributor.authorBaillot, Sylvain
dc.contributor.authorMallet, Vincent
dc.contributor.authorRehm, Jürgen
dc.date.accessioned2022-04-05T13:55:16Z
dc.date.available2022-04-05T13:55:16Z
dc.date.issued2017-07
dc.description.abstractBackground: Evidence on diseases caused by or associated with alcohol use disorders (AUDs) has been based on two meta-analyses including rather dated studies. The objective of this contribution was to estimate the risks of all-cause mortality and alcohol-attributable disease categories depending on a diagnosis of AUDs in a national sample for France. Methods: In a national retrospective cohort study on all inpatient acute and rehabilitation care patients in Metropolitan France 2008–2012 (N = 26,356,361), AUDs and other disease categories were identified from all discharge diagnoses according to standard definitions, and we relied on in-hospital death for mortality (57.4% of all deaths). Results: 704,803 (2.7%) patients identified with AUDs had a threefold higher risk of death (HR = 2.98; 95% CI: 2.96–3. 00) and died on average 12.2 years younger (men: 10.4, 95% CI: 10.3–10.5; women: 13.7, 95% CI: 13.6–13.9). AUDs were associated with significantly higher risks of hospital admission for all alcohol-attributable disease categories: digestive diseases, cancers (exception: breast cancer), cardiovascular diseases, dementia, infectious diseases, and injuries. Elevated risks were highest for liver diseases that were associated with about two-third of deaths in patients with AUDs (men: 64.3%; women: 71.1%). Conclusions: AUDs were associated with marked premature mortality and higher risks of alcohol-attributable disease categories. Our results support the urgent need of measures to reduce the burden of AUDs.en
dc.identifier.bibliographicCitationSchwarzinger, M., Thiébaut, S. P., Baillot, S., Mallet, V., & Rehm, J. (2017). Alcohol use disorders and associated chronic disease – a national retrospective cohort study from France. BMC Public Health, 18 (1). https://doi.org/10.1186/s12889-017-4587-yes
dc.identifier.doihttps://doi.org/10.1186/s12889-017-4587-y
dc.identifier.issn1471-2458
dc.identifier.publicationfirstpage1es
dc.identifier.publicationissue1es
dc.identifier.publicationlastpage9es
dc.identifier.publicationtitleBMC Public Health (BMC Public Health)es
dc.identifier.publicationvolume18es
dc.identifier.urihttps://hdl.handle.net/10016/34528
dc.identifier.uxxiAR/0000029483
dc.language.isoenges
dc.publisherBMCes
dc.rights© The Author(s).es
dc.rightsAtribución 3.0 España*
dc.rights.accessRightsopen accesses
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subject.ecienciaEconomíaes
dc.subject.otherAlcohol use disordersen
dc.subject.otherBurden of diseaseen
dc.subject.otherMortalityen
dc.subject.otherNon-communicable diseaseen
dc.subject.otherRisk factoren
dc.titleAlcohol use disorders and associated chronic disease - A national retrospective cohort study from Franceen
dc.typeresearch article*
dc.type.hasVersionVoR*
dspace.entity.typePublication
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