Publication:
New insights on the self-organization of PEG/alpha-cyclodextrin- based Polyrotaxanes in solution: an experimental and theoretical study

Thumbnail Image
Identifiers
URI: https://hdl.handle.net/10016/24481
ISSN: 1521-3935
DOI: http://dx.goi.org/10.1002/macp.201300370
UXXI: AR/0000014414
Files
new_MCP_2013_ps.pdf (1.95 MB)
Publication date
2013-10-10
Defense date
Authors
Advisors
Tutors
Journal Title
Journal ISSN
Volume Title
Publisher
WILEY
Impact
Google Scholar
Export
Research Projects
Organizational Units
Journal Issue
Abstract
Size exclusion chromatography coupled with light scattering (SEC/MALS), dynamic light scattering (DLS), steady-state and time-resolved fluorescence, as well as molecular dynamics (MD) simulations are used to study the behavior of several poly(ethylene glycol) (PEG)/α-cyclodextrins (αCDs) polyrotaxanes (PRs) in solution. The number of CD units in any of the PRs studied is always smaller than that required to saturate the PEG chains. These PRs seem to aggregate in dimethyl sulfoxide (DMSO) solution. The presence of hairpins in the non-saturated PRs contributes to diminishing their expected large dimensions. Intra- and inter­molecular interactions and forces responsible for hairpins and aggregation are investigated.
Description
Keywords
Fluorescence, Molecular dynamics, Poly(ethylene glycol) (PEG), Polyrotaxane, Size exclusion chromatography
Bibliographic citation
Macromolecular Chemistry and Physics, 2013, 214 (24), pp.: 2801-2812.
Collections
DCIMIQ - CIMIQ - PC - Artículos de Revistas