Publication: Automatic Cardiac Gating of Small-animal PET from List-mode Data
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2011-07
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Fully 3D
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Abstract
This work presents a method to obtain automatically the cardiac gating signal in a PET study of rats, by employing the variation with time of the counts in the cardiac region, that can be extracted from list-mode data. In an initial step, the cardiac region is identified in the image space by backward-projecting a small fraction of the acquired data and studying the variation with time of the counts in each voxel inside said region, with frequencies within 2 and 8 Hz. The region obtained corresponds accurately to the left-ventricle of the heart of the rat. In a second step, the lines-of-response (LORs) connected with this region are found by forward-projecting this region. The time variation of the number of counts in these LORs contains the cardiac motion information that we want to extract. This variation of counts with time is band-pass filtered to reduce noise, and the time signal so obtained is used to create the gating signal. The result was compared with a cardiac gating signal obtained from an ECG acquired simultaneously to the PET study. Reconstructed gated images obtained from both gating information are similar. The method proposed demonstrates that valid cardiac gating signals can be obtained for rats from PET list-mode data.
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Proceedings of: 11th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine (Fully 3D 2011). 11-15 July, 2011, Potsdam, Germany.
Keywords
Image reconstruction, Positron emission tomography, Cardiac Gating, Self-gating, Automatic gating, List mode data
Bibliographic citation
Fully 3D 2011 Proceedings: 11th International Meeting on Fully Three-Dimensional Image Reconstruction in Radiology and Nuclear Medicine. July 11 − July 15, 2011, Potsdam, Germany. pp. 206-209