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Clinical outcomes after the use of complete autologous oral mucosa equivalents: preliminary cases

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URI: http://hdl.handle.net/10016/18924
ISSN: 2212-4403
DOI: 10.1016/j.tripleo.2011.07.030
UXXI: AR/0000014194
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clinical_OSOMOPOR_2012_ps.pdf (14.21 MB)
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2012-05
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Elsevier
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Abstract
Objective. Previously, we reported how to obtain complete autologous oral mucosa equivalents (CAOMEs) composed of an autologous plasma scaffold and fibroblasts together with immature keratinocytes able to build an oral epithelium with a structure similar to that of the oral mucosa. In this study, we present the clinical outcomes after applying our CAOMEs as grafts. Study Design. Four patients who needed a CAOME to restore a defect of oral mucosa were selected. Two of the patients suffered from ankyloglossia, and the other 2 required a restoration of the keratinized gum of the alveolar rim. To assess the outcomes, the scale designed by Ewers et al. was used.
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Tissue-Engineered mucosa, Reconstruction transplants, Scaffold, Sheets, Tongue, Skin
Bibliographic citation
Oral surgery, oral medicine, oral pathology and oral radiology, Vol. 113, nº 5 (May 2012), pp. 4-11
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DBIAB - TERMEG - Journal Articles