Archivo Abierto Institucional de la Universidad Carlos III de Madrid >
Departamento de Bioingeniería e Ingeniería Aeroespacial: Bioingeniería >
DBIAB - Journal Articles >
Please use this identifier to cite or link to this item:
|Title: ||Initial results from a PET/planar small animal imaging system|
|Author(s): ||Siegel, Stefan|
Vaquero, Juan José
Gandler, William R.
Eckelman, W. C.
Green, Michael V.
|Issued date: ||Jun-1999|
|Citation: ||IEEE Transactions on Nuclear Science, vol. 46, n. 3, jun. 1999. Pp. 571-575|
|Abstract: ||A pair of stationary, opposed scintillation detectors in time coincidence is being used to create planar projection or tomographic images of small animals injected with positronemitting radiotracers. The detectors are comprised of arrays of individual crystals of bismuth germanate coupled to position-sensitive photomultiplier tubes. The system uses FERA (LeCroy Research Systems) charge-sensitive ADCs and a low cost digital YO board as a E R A bus-to-host bridge. In projection mode, the animal is placed within the 55 mm x 45 mm useful field-of-view of the detectors and images are formed from coincidence lines that fall close to the normals of both detectors. In tomographic mode, the animal is placed on a rotation stage between the detectors and rotated around a vertical axis to acquire all possible lines-of-response. Tomographic images are then reconstructed from those lines falling within a user-specified angle of each detector normal. In mice, the system is capable of high-speed, whole-body dynamic projection imaging, and whole body tomographic imaging of slowly varying tracer distributions. An ECG gating capability is also available for evaluating cardiac function. This system is currently being used to study tracer transport in normal and genetically engineered mice.|
|Publisher version: ||http://dx.doi.org/10.1109/23.775581|
|Rights: ||© IEEE|
|Appears in Collections:||DBIAB - Journal Articles|
Items in E-Archivo are protected by copyright, with all rights reserved, unless otherwise indicated.