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Publication Qualitative disorder measurements from backscattering spectra through an optical fiber(OSA, 2020-10-01) Fernández Sánchez, Rafael; Marcos Vidal, Asier; Gallego, S.; Beléndez, A.; Desco Menéndez, Manuel; Ripoll Lorenzo, Jorge; Comunidad de Madrid; European Commission; Ministerio de Economía y Competitividad (España); Ministerio de Ciencia, Innovación y Universidades (España)In the processes related to the development of cancer, there are different genetic and epigenetic events involved that result in structural changes of the affected cells. In the early stages of the disease, these changes occur at the nanoscale, remaining undetectable by conventional light microscopy, due to diffraction-limited resolution (~250 - 550 nm). In this sense, a technique termed partial wave spectroscopy (PWS) allows the detection of these nanostructural changes by measuring a statistical parameter called disorder strength (Ld). PWS uses a combination of a tunable filter and a camera to acquire the backscattering spectra for each pixel on the image. In this paper, we study and validate the possibility of obtaining a qualitative measurement of the disorder using the spectrum of the averaged spatial information. Instead of using spatial information and measuring sequentially spectral ranges, we measure the backscattered signal gathered by an optical fiber by means of a spectrograph. This will allow this method to be applied in systems where it is not possible to acquire a complete high resolution image for many spectral bands, while significantly enhancing speed.Publication In-line high resolution PET and 3T MRI hybrid device for preclinical multimodal imaging(Springer, 2014-05) Vaquero López, Juan José; Montesinos, P.; Cusso Mula, Lorena; García Vázquez, Verónica; Desco Menéndez, ManuelPublication Fully automatic scoring or sister-chromatid ex-changes(Elsevier, 1993) García Sagredo, José Miguel; Piper, J.; Ji, L.; Vaquero López, Juan José; Vázquez, Y.Publication A high performance prhoswich detector module for small animal PET(Society of Nuclear Medicine, 2000) Vaquero López, Juan José; Barbosa, F. J.; Seidel, Jürgen; Green, Michael V.Publication Automatic system for FISH cytogenetic analysis(Karger, 1997) Santos, Andrés; Ortiz de Solórzano, Carlos; Malpica, Norberto; Vaquero López, Juan José; Pozo, Francisco del; García Sagredo, José MiguelPublication Fat composition assessment by 1H and 13C spectroscopy in mice(International Society for Magnetic Resonance in Medicine, 2009) Benito, M.; Fernández, Susana; Montesinos, P.; Vaquero López, Juan José; Chavarrías, Cristina; Desco Menéndez, ManuelPublication Automatic segmentation of FISH clustered nuclei using morphological watersheds(Wiley, 1996-03) Ortiz de Solórzano, Carlos; Malpica, Norberto; Vaquero López, Juan José; Santos, Andrés; Pozo, Francisco del; García Sagredo, José MiguelPublication Automated FISH spots counting in interphase nuclei(IOS Press, 1994) García Sagredo, José Miguel; Pascual, J.; Ortiz de Solórzano, C.; Vaquero López, Juan José; Pozo, Francisco delPublication Brain metabolism in lewis and fischer 344 rats after morphine self-administration and extinction: a PET imaging study(The College on Problems of Drug Dependence, 2010) Ambrosio, Emilio; Montoya, Gonzálo L.; Soto Montenegro, Mª Luisa; García Vázquez, Verónica; Pascau González-Garzón, Javier; Miguéns, Miguel; Higuera Matas, Alejandro; Olmo, Nuria del; Vaquero López, Juan José; García Lecumberri, Carmen; Desco Menéndez, ManuelPublication Iodinated contrast agents for improving tumor imaging and quantification in rodents(World Molecular Imaging Society, 2008) Soto Montenegro, Mª Luisa; Epifano, Carolina V.; Vaquero López, Juan José; Casal, Ignacio; Desco Menéndez, ManuelPublication Co-Planar FMT-CT(World Molecular Imaging Society, 2008) Aguirre, Juan; Sisniega, Alejandro; Ripoll Lorenzo, Jorge; Desco Menéndez, Manuel; Vaquero López, Juan JoséPublication Computed tomography assesment in the characterization of mouse model for Costello Syndrome(World Molecular Imaging Society, 2008) Soto Montenegro, Mª Luisa; Mulero, Francisca; Reig, Santiago; Schumahmacher, Alberto J.; Guerra, Carmen; Vaquero López, Juan José; Barbacid, Mariano; Desco Menéndez, Manuel