Publication: NEMA NU 4-2008 Performance measurements of two commercial small-animal PET scanners: clearPET and rPEAT-1
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2011-02
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Tutors
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IEEE
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Abstract
In this work, we compare two commercial positron emission tomography (PET) scanners installed at CIEMAT (Madrid, Spain): the ClearPET and the rPET-1. These systems
have significant geometrical differences, such as the axial field
of view (110 mm on ClearPET versus 45.6 mm on rPET-1), the
configuration of the detectors (whole ring on ClearPET versus
one pair of planar blocks on rPET-1) and the use of an axial
shift between ClearPET detector modules.We used an assessment procedure that fulfilled the recommendations of the National Electrical Manufacturers Association (NEMA) NU 4-2008 standard.
The methodology includes studies of spatial resolution, sensitivity, scatter fraction, count losses and image quality. Our experiments showed a central spatial resolution of 1.5 mm (transaxial), 3.2 mm (axial) for the ClearPET and 1.5 mm (transaxial), 1.6 mm (axial) for the rPET-1, with a small variation across the transverse
axis on both scanners (~1 mm). The absolute sensitivity at the centre of the field of view was 4.7% for the ClearPET and 1.0% for the rPET-1. The peak noise equivalent counting rate for the mouse-sized phantom was 73.4 kcps reached at 0.51 MBq/mL on the ClearPET and 29.2 kcps at 1.35 MBq/mL on the rPET-1. The recovery coefficients measured using the image quality phantom ranged from 0.11 to 0.89 on the ClearPET and from 0.14 to 0.81 on the rPET-1. The overall performance shows that both the ClearPET and the rPET-1 systems are very suitable for preclinical research and imaging of small animals
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Image quality assessment, Performance evaluation, PET, Small-animal imagers
Bibliographic citation
IEEE Transactions on Nuclear Science, feb. 2011, vol. 58, n. 1, p. 58-65