Publication:
Atlas-based automated positioning of outer volume suppression slices in short-TE 3D MR spectroscopic imaging of the human brain

Simple item page
dc.affiliation.dptoUC3M. Departamento de Teoría de la Señal y Comunicacioneses
dc.contributor.authorYung, Kaung-Ti
dc.contributor.authorZheng, Weili
dc.contributor.authorZhao, Chenguang
dc.contributor.authorVan der Kouwe, André
dc.contributor.authorMartínez-Ramón, Manel
dc.contributor.authorPosse, Stefan
dc.date.accessioned2011-07-05T14:02:57Z
dc.date.available2011-07-05T14:02:57Z
dc.date.issued2011-04-05
dc.description.abstractSpatial suppression of peripheral lipid-containing regions in volumetric MR spectroscopic imaging (MRSI) of the human brain requires placing large numbers of outer volume suppression (OVS) slices, which is time consuming, prone to operator error and may introduce subject-dependent variability in volume coverage. We developed a novel, computationally efficient atlas-based approach for automated positioning of up to 16 OVS slices and the MRSI slab. Standardized positions in MNI atlas space were established offline using a recently developed iterative optimization procedure. During the scanning session, positions in subject space were computed using affine transformation of standardized positions in MNI space. This atlas-based approach was characterized offline using MPRAGE data collected in 11 subjects. The method was further validated in 14 subjects on a clinical 3T scanner using 3D short TE (15-20ms) Proton-Echo-Planar-Spectroscopic-Imaging (PEPSI) in upper cerebrum. Comparison of manual and automatic placement using 8 OVS slices demonstrated consistent MRSI volume selection and comparable spectral quality with similar degree of lipid suppression and number of usable voxels. Automated positioning of 16 OVS slices enabled larger volume coverage, while maintaining similar spectral quality and lipid suppression. Atlas-based automatic prescription of short TE MRSI is expected to be advantageous for longitudinal and cross sectional studies
dc.description.sponsorshipThis work was supported in part by the MIND Research Network (DOE Grant No. DE-FG02-99ER62764) and the University of New Mexico School of Medicine Brain and Behavioral Illness Signature Program.
dc.description.statusPublicado
dc.format.mimetypeapplication/pdf
dc.identifier.bibliographicCitationMagnetic Resonance in Medicine, (2011), 66(4), 911-922.
dc.identifier.doi10.1002/mrm.22887
dc.identifier.issn1522-2594
dc.identifier.publicationfirstpage911
dc.identifier.publicationissue4
dc.identifier.publicationlastpage922
dc.identifier.publicationtitleMagnetic Resonance in Medicine
dc.identifier.publicationvolume66
dc.identifier.urihttps://hdl.handle.net/10016/11696
dc.language.isoeng
dc.publisherWiley-Liss
dc.relation.publisherversionhttp://dx.doi.org/10.1002/mrm.22887
dc.rights© Wiley-Liss
dc.rights.accessRightsopen access
dc.subject.ecienciaTelecomunicaciones
dc.subject.otherOuter Volume Suppression
dc.subject.otherMR spectroscopic imaging
dc.subject.otherBrain imaging
dc.titleAtlas-based automated positioning of outer volume suppression slices in short-TE 3D MR spectroscopic imaging of the human brain
dc.typeresearch article*
dc.type.hasVersionSMUR*
dspace.entity.typePublication
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
OVS with spatial normalization 051710 submitted MRM MRM-10-11638.pdf
Size:
509.7 KB
Format:
Adobe Portable Document Format
Download
Collections
DTSC - G2PI - Artículos de Revistas