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Improved image reconstruction in small animal PET using a priori estimation of single-pixel events

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dc.affiliation.dptoUC3M. Departamento de Bioingenieríaes
dc.affiliation.grupoinvUC3M. Grupo de Investigación: Biomedical Imaging and Instrumentation Groupes
dc.affiliation.grupoinvUC3M. Grupo de Investigación: BSEL - Laboratorio de Ciencia e Ingeniería Biomédicaes
dc.contributor.authorEspaña, Samuel
dc.contributor.authorHerraiz, J. L.
dc.contributor.authorVicente, Esther
dc.contributor.authorHerranz, Elena
dc.contributor.authorVaquero López, Juan José
dc.contributor.authorDesco Menéndez, Manuel
dc.contributor.authorUdías, José Manuel
dc.date.accessioned2011-10-05T13:44:01Z
dc.date.available2011-10-05T13:44:01Z
dc.date.issued2007
dc.descriptionProceeding of: 2007 IEEE Nuclear Science Symposium Conference Record (NSS '07), Honolulu, Hawaii, USA, Oct. 27 - Nov. 3, 2007
dc.description.abstractMost small animal PET scanners are based on arrays of pixelated scintillators crystals. As the read-out of individual pixels would be too expensive, identification of the crystal of interaction is usually made by center of energy methods based for instance on Anger logic. This allows for a reduction in the number of signals to be acquired, but prevents the identification of multi-hit events, that is, events in that one (or several) photon produces several hits in the detector, thus blurring the correct positioning of the interaction. Improving the identification of the pixel of interaction is pursued in this work by combining all the information acquired by the scanner without increasing the number of signals. The probability for every individual event for being single or multi-pixel is estimated from the XY positioning and energy information. This probability is fed into a 3D-OSEM iterative statistical reconstruction method. Every coincidence event detected may be analyzed combining information such as deposited energy, PMT XY location, time difference between both singles of the coincidence and coincidence and single rates, if available. With the proposed method, improved peak/noise ratio and better resolution are obtained without the introduction of additional hardware.
dc.description.sponsorshipThis work has been partially funded by projects TEC2004-07052-C02 of Ministerio de Educación y Ciencia and CDTEAM, program CENIT, Ministerio de Industria, Spain.
dc.format.mimetypeapplication/pdf
dc.identifier.bibliographicCitation2007 IEEE Nuclear Science Symposium Conference Record, 2007, vol. 5, p. 3876 - 3880
dc.identifier.doi10.1109/NSSMIC.2007.4436965
dc.identifier.isbn978-1-4244-0922-8
dc.identifier.issn1082-3654
dc.identifier.publicationfirstpage3876
dc.identifier.publicationlastpage3880
dc.identifier.publicationtitle2007 IEEE Nuclear Science Symposium Conference Record
dc.identifier.publicationvolume5
dc.identifier.urihttps://hdl.handle.net/10016/12232
dc.language.isoeng
dc.publisherIEEE
dc.relation.eventdateOct. 27 - Nov. 3, 2007
dc.relation.eventplaceHonolulu, Hawaii, USA
dc.relation.eventtitle2007 IEEE Nuclear Science Symposium Conference Record (NSS '07)
dc.relation.publisherversionhttp://dx.doi.org/10.1109/NSSMIC.2007.4436965
dc.rights© IEEE
dc.rights.accessRightsopen access
dc.subject.ecienciaBiología y Biomedicina
dc.titleImproved image reconstruction in small animal PET using a priori estimation of single-pixel events
dc.typeconference paper*
dspace.entity.typePublication
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